The Design of Animal Experiments
Reducing the use of animals in research through better experimental design
- Michael Festing - University of London, London, UK
- Philip Overend - GlaxoSmithKline, UK
- Mario Cortina Borja - University College London, UK
- Manuel Berdoy - University of Oxford, UK
Laboratory Animal Handbooks
The Design of Animal Experiments is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively and/or to improve their ability to communicate with professional statisticians when necessary. It covers all randomised controlled experimental designs likely to be needed in laboratory animal research, with worked examples showing how they can be statistically analysed. It suggests the more widespread use of randomised block designs and shows how both males and females can be included in an experiment without the need to increase the total number of animals by using factorial designs. It also includes guidance on the choice of experimental animals. The book covers the learning outcomes of Module 10 and part (ii) of Module 11 of education and training under Directive 2010/63/EU.